Bioluminescent Stem-Loop Probes (BLSP)
Our research focuses on the development of novel bioluminescent SLPs (BSLPs) that provide unprecedented sensitivity and selectivity for RNA sensing and demonstrate its application in sensing of viral persistency. The development of a BSLP would enhance sensitivity of current SLP-based detection systems by retaining the rugged versatility and broad applicability of its fluorescent counterparts while exhibiting low background and high detection sensitivity and the negligible effect of matrix on biouminescne signal will provide for rapid detection of RNA using BSLPs in any sample matrix.
